Analysis of Biological Networks: Genetic Interaction Networks
نویسندگان
چکیده
Genetic interaction (GI) is a logical interaction between two genes that affects a phenotype some observable characteristics of the organism. Knowledge of genetic interactions can assist in identifying pathways, recognize gene function and find potential drug targets. Modern research tools enable performing large-scale mapping of GIs. In this scribe, the following subjects will be discussed: • Types of genetic interactions (section 2). • The technique of deriving genetic interactions (Synthetic Genetic Array) and its accuracy (section 3). • Characteristic properties of GIs (section 4). • The concept of chemical genetic interaction (CGI) (section 5). • Interrelation with PPI data (section 6).
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